Protein Info for MMP_RS05320 in Methanococcus maripaludis S2

Annotation: NFACT family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 680 PF05833: NFACT_N" amino acids 8 to 459 (452 residues), 221.5 bits, see alignment E=2.1e-69 PF05670: NFACT-R_1" amino acids 491 to 595 (105 residues), 100.2 bits, see alignment E=1e-32

Best Hits

Swiss-Prot: 55% identical to Y1625_METJA: Uncharacterized protein MJ1625 (MJ1625) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP1028)

Predicted SEED Role

"COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYG3 at UniProt or InterPro

Protein Sequence (680 amino acids)

>MMP_RS05320 NFACT family protein (Methanococcus maripaludis S2)
MKTEMTNVDISVAVSELQKVINGKLDKAFLVNNQDGKELILKVHIPEIGSREIAIGLGKY
KYMTLTEYEREKPRNPPSFVMLLRKHLKNIKITSVAQHNFDRIVIFNFEWNELKYKLIIE
LFGDGNAILLDSEDKIILPLKIERWSTRKIVPKEIYKFPPQKDLDPKNLDYSLAKKLFIE
EFEKEENKDTEVVRIISRTFGLAGVYSEEICLNSEIDKNLKNPKNEEIEKLFEGSKSFFK
KVFGELKPKSTLKNGEFVNIDPIDLKIHENLKENEIKHYESFLTALDEYFSRFIMKKEIK
QAESKLQKLVKKQERILKSQLDTKDKYEKQSVSNHKRGDLIYANYSLVDEIVSTIKDARE
KMDWNGIKNVIKENKTHPILSKIINVNEKNAELTLKLSADYGNGLIEDSVPVDLRKNAFE
NADIVYQKSKKFKNKVQGVIEALKISEKKLAELKEKEKLDSEVFKEKEEKIKKKERKVLK
WYEKLKWTVIGGYLIVAGKDATTNEMLIKRYVEKNDIVFHTLMEGAPFTIIRTEGSEEIP
DENILFEVAKFAASHSRAWKLGIGSADVYWVRPDQISKTAESGEYLKKGAFVIRGKRNFI
RSAALELGIGIINYDGKLRLTTAPESVAKENFEKCILLKPGKLKKSDLVKELLKEFSDFE
VDDEDILRALPPGESEIKLK