Protein Info for MMP_RS05115 in Methanococcus maripaludis S2

Annotation: 50S ribosomal protein L11 methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 295 PF02475: Met_10" amino acids 186 to 260 (75 residues), 28 bits, see alignment E=2.7e-10 PF06325: PrmA" amino acids 188 to 253 (66 residues), 32.4 bits, see alignment E=1e-11 PF03602: Cons_hypoth95" amino acids 195 to 245 (51 residues), 30.2 bits, see alignment 5.3e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0988)

Predicted SEED Role

"RNA methyltransferase related protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYK3 at UniProt or InterPro

Protein Sequence (295 amino acids)

>MMP_RS05115 50S ribosomal protein L11 methyltransferase (Methanococcus maripaludis S2)
MLSKGAVIDKLKSYKPCENCNGPISKTVSISDLNLDKRKRNCVCGNSQLDDVMLDVLNLM
SEYNELQNTDLKDVTLRDAGTPLVEIGYPLKYLPVVSNDELIVMKDVSKACATEILKIPE
VKGVISNNSKNNSFNRVEDSGEVNALIAGDDFRCDIFVLKSIMDCVVICKNQSKVHIEFP
RPFNPKIAKIDRLNLKGKVVVDGFCGSGTLGLAALKKGAKKVIFSDINPHALKDVIYNLK
LNFSKEVFDRIEIINSDFLNLDIVGDVCFVDLFPHMDKEPFLNKAKTISKQVVLI