Protein Info for MMP_RS04695 in Methanococcus maripaludis S2

Annotation: selenide water dikinase SelD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 TIGR00476: selenide, water dikinase" amino acids 8 to 285 (278 residues), 222.7 bits, see alignment E=3.3e-70 PF00586: AIRS" amino acids 37 to 143 (107 residues), 68.6 bits, see alignment E=6.1e-23 PF02769: AIRS_C" amino acids 157 to 321 (165 residues), 67.8 bits, see alignment E=1.3e-22

Best Hits

Swiss-Prot: 100% identical to SELD_METMP: Selenide, water dikinase (selD) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K01008, selenide, water dikinase [EC: 2.7.9.3] (inferred from 97% identity to mmx:MmarC6_1751)

Predicted SEED Role

"Selenide,water dikinase (EC 2.7.9.3) @ selenocysteine-containing" (EC 2.7.9.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.9.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P60820 at UniProt or InterPro

Protein Sequence (335 amino acids)

>MMP_RS04695 selenide  water dikinase SelD (Methanococcus maripaludis S2)
MVTLHG*ACKLPDTELENLVKGIISEDDLKHAKVGLGDDAAVVIKNGMAIVKTIDVFTPI
VDDPYLQGRIAACNSTSDVYAMGISEIIGGLVFLGIPPELPVPVAKKMLQGFQDFCREND
TTIIGGHTILNPWPLIGGSITGVGKEEDILTKAGCKNGDVLILTKPLGNQSAMALSRVTE
EFEDLIDIPKEEQKYIFEKTIELMTTSNRIALLHLRELENELGEKIANAMTDVTGFGILG
HSQEMAEQSDVEIEISCLPVIKGTPELASLFGHALCSGKGAETAGGLLISTKPEYKDKLI
QKFKENNVYAFEVGKIVNNGVGIAKLSENVEILEI