Protein Info for MMP_RS04425 in Methanococcus maripaludis S2

Annotation: APC family permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 transmembrane" amino acids 9 to 32 (24 residues), see Phobius details amino acids 38 to 57 (20 residues), see Phobius details amino acids 87 to 109 (23 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details amino acids 147 to 168 (22 residues), see Phobius details amino acids 184 to 206 (23 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 268 to 294 (27 residues), see Phobius details amino acids 314 to 337 (24 residues), see Phobius details amino acids 343 to 363 (21 residues), see Phobius details amino acids 375 to 406 (32 residues), see Phobius details PF13520: AA_permease_2" amino acids 6 to 395 (390 residues), 68 bits, see alignment E=7.8e-23 PF00324: AA_permease" amino acids 43 to 409 (367 residues), 37.1 bits, see alignment E=1.6e-13

Best Hits

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 100% identity to mmp:MMP0850)

Predicted SEED Role

"Amino acid permease family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYX9 at UniProt or InterPro

Protein Sequence (417 amino acids)

>MMP_RS04425 APC family permease (Methanococcus maripaludis S2)
MSSKKLGPYTLSGLIVGPILGSGIVIIPPIVYDILKDYSIFAWVIMMTIGGVFAYFASKL
CLKFPGDSGLTEVVGHSFGKSYKNLNAYYLLIAMAMAPLVVIMVAGEYLSVLFSNYAFGA
EFYSAVLMLIGGVILSRNISSVGKISMLISTVISTILVVGGLFTILFYRKDALFTGTGIS
TIDVGYSFLIMFWSIIGWEILGNYSLEVENPEKTIPKAALVSVIAMSIVYLIVSGALQVL
DIGKLGLIDPISGISLILYPLFGQYSSIILSLTITGLCLCSFLMLIGGASRLVYAQAKDG
VFPKIFKYRSNTNAPLSAVLLMVFANFLTLFAVYFNLISFNEIIAAVNAFLITNIIMAAV
ASIKVFENVMEKGFAVFLLVSFLLMFLFSSKMVILIILAMLFGTVVYTLKNNNYNIK