Protein Info for MMP_RS04335 in Methanococcus maripaludis S2

Annotation: GTP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 302 PF02492: cobW" amino acids 6 to 177 (172 residues), 141 bits, see alignment E=3.4e-45 PF07683: CobW_C" amino acids 216 to 301 (86 residues), 42.4 bits, see alignment E=5.3e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0833)

Predicted SEED Role

"Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LYZ6 at UniProt or InterPro

Protein Sequence (302 amino acids)

>MMP_RS04335 GTP-binding protein (Methanococcus maripaludis S2)
VVKIDVVSGYLGSGKTTFIKHLLNACGNEKVIVIENEFGEIAIDGDLIKNEGFEVYELQQ
GCICCSIRSNFIEALGKIVDEFEPDRIIVEPTGMGLLSEIIGILSIPKIKQISEINSLTT
VVDAENYLEEVEGFGEFFKDQIKNADRLIISKAQFMNYQEIDKILSSLRELNPNSLIVTQ
NWEFMAPEEFLKILDNSSENSGKIYRGNVEAAMKGVSSIGLEFTESFKEKDIENIILELK
SGKYGQIMRGKGFLNIDDKTMEFNYVGNDCKLELLNTKKDQKICIIGKNLEKEAVSELFN
NL