Protein Info for MMP_RS03940 in Methanococcus maripaludis S2

Annotation: McrC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 426 PF10117: McrBC" amino acids 65 to 382 (318 residues), 369 bits, see alignment E=8.8e-115

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0756)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZ73 at UniProt or InterPro

Protein Sequence (426 amino acids)

>MMP_RS03940 McrC family protein (Methanococcus maripaludis S2)
MNNLKDITLNEFQYLIKGLNDEPHDRGFVINKHIFEKLELFVLKSKENSGCEFLRLTSLN
GRKALQALNYVGIIKLKNGPTIEILPKINNDHISNEKVRRIFLKMLKSLKNAPFKEFGDA
SLKTHKMKLNEIFIKIFLDDLDVLVKNGLKSDYISIEDNLNVLKGKIKFNEHISKNYIHK
ERFYVNYDEFIRNRPENRIIKSTIKYLLKNSSLNSNLKRINEFLFIMDAIPESKNLEKDF
AACVNNRLMTDYKKIIPWCKVFLKNESFTNFKGDEIAYALLYPMEKIFESYLTEEFKKSG
KFETIVSQGNGYFLAKHKNEGIFRLKPDIYAETSSKKYIMDAKWKILNSDKNKNYGISQN
DMYQLLSYAVVYGCNELRLLYPKSKDFKRILEFEYNNSINYKEKISLKIIPIDLERNIAD
QIGFLL