Protein Info for MMP_RS03750 in Methanococcus maripaludis S2

Annotation: ACT domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 141 PF19571: ACT_8" amino acids 1 to 138 (138 residues), 119.6 bits, see alignment E=1.8e-38 PF01842: ACT" amino acids 5 to 60 (56 residues), 32.9 bits, see alignment E=8.9e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0716)

Predicted SEED Role

"Amino acid-binding ACT" in subsystem Aromatic amino acid interconversions with aryl acids

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZB3 at UniProt or InterPro

Protein Sequence (141 amino acids)

>MMP_RS03750 ACT domain-containing protein (Methanococcus maripaludis S2)
MIIKQLSVFLENKSGRLNEVTEILEKAGINISALSVADTSDYGILRMVVSNPDLALKILK
ENRFSVSLTDVLCICIPNKIGSLSKTINILSKENISIDYVYAFSMNDKALAVLRTEDIQK
GIDVLKEHDTEVLDAEDIYGI