Protein Info for MMP_RS03140 in Methanococcus maripaludis S2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 476 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF21667: Nop5_N" amino acids 1 to 121 (121 residues), 178.2 bits, see alignment E=5.5e-57 PF01798: Nop" amino acids 137 to 359 (223 residues), 234.1 bits, see alignment E=1.6e-73

Best Hits

Swiss-Prot: 47% identical to Y694_METJA: Uncharacterized NOP5 family protein MJ0694 (MJ0694) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0596)

Predicted SEED Role

"rRNA biogenesis protein Nop5/Nop56" in subsystem Ribosome biogenesis archaeal

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZM8 at UniProt or InterPro

Protein Sequence (476 amino acids)

>MMP_RS03140 hypothetical protein (Methanococcus maripaludis S2)
MLFIAFAPFGAFALEANSKNDGYSLDDIKYYKIFENEDIPKIMYALRQGDFEIIAELKNE
WEIEEEDVSFEYTTSKNPLGELIRDNLYELGQKYEVFEDESDFVSKMNVWATAFTKSMMK
KSSEQKDKLIVQTVNALDNLDETLNLFSERLREWYSLYFPEMDNIVKKHDIYVSLVSEYG
DREEYTRTKLKKTMPSNVARTISLAAKESMGADVSEFDLKIMKNLADEIKSMYEYRESLQ
EYLETSMNEIAPNLTKVAGASLGARLISLAGGIERLLRLPASTIQVIGAEKALFAHLRER
ALPPKHGVIFQHPLIQGSPWWIHGKIARAISCKISIAIRADAFGNDISDMLIEDMNKKVA
EIKEKFPEPTRKRRPRPDTRSFGNKGGQDRDRRSQGDRKPSGNRGDSKKGGKPFGKKPAG
KDDRRDNRKGDRKPFGGKPKNSGNQPPKERSGEKRRDSTKKVKAERKVIGKTSSQN