Protein Info for MMP_RS03025 in Methanococcus maripaludis S2

Annotation: molybdenum cofactor guanylyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 PF12804: NTP_transf_3" amino acids 4 to 156 (153 residues), 93.5 bits, see alignment E=8.2e-31

Best Hits

KEGG orthology group: K03752, molybdopterin-guanine dinucleotide biosynthesis protein A (inferred from 100% identity to mmp:MMP0573)

Predicted SEED Role

"Molybdopterin-guanine dinucleotide biosynthesis protein MobA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZQ1 at UniProt or InterPro

Protein Sequence (214 amino acids)

>MMP_RS03025 molybdenum cofactor guanylyltransferase (Methanococcus maripaludis S2)
MISAIILSGGKAERMGGEKSFRKSGNKYLIENIADMLIEMEIPFVTVFKNPRFMEKPEEE
IEKQLYYYKKYHQTITWDFVPGMGPLIGMLSGMLNTKSQWVFLVPCDMPFITEESIINLL
SFIKEAELNGYDCIVPKHKNGFIEPLFSLYHISSVNVLGMVVEEMLEQNRSFPIRRLIDE
LNPLYVDVDKIDKTCDIFINLNTLKELENACFDR