Protein Info for MMP_RS02955 in Methanococcus maripaludis S2

Annotation: DJ-1/PfpI family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01965: DJ-1_PfpI
  • amino acids 4 to 167 (164 residues), 140 bits, E=3.3e-45

Best Hits

Swiss-Prot: 58% identical to Y967_METJA: Uncharacterized protein MJ0967 (MJ0967) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K05520, protease I [EC: 3.2.-.-] (inferred from 100% identity to mmp:MMP0559)

Predicted SEED Role

"ThiJ/PfpI family protein"

KEGG Metabolic Maps

• Glycosaminoglycan degradation

Isozymes

Compare fitness of predicted isozymes for: 3.2.-.-

Use Curated BLAST to search for 3.2.-.-

Sequence Analysis Tools

See Q6LZR5 at UniProt or InterPro

Protein Sequence (171 amino acids)

>MMP_RS02955 DJ-1/PfpI family protein (Methanococcus maripaludis S2)
VAIVMVIAPEKFRDEELFEPLQVFQSKNIATQVVSTTTGQHKGVLGRVMTTTKTIEGVNP
DDFDAIVIVGGGGSRDYLWNNEKLLELLKEFNSMGKITAAICISPAVLAQAGLLTGKKAT
VFPDDEAIAVLQQKGAIYLDEAVILDGTVITGRNPDAAKEFGLKIAEALGK