Protein Info for MMP_RS02910 in Methanococcus maripaludis S2

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 264 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF00497: SBP_bac_3" amino acids 45 to 261 (217 residues), 117 bits, see alignment E=2.6e-38

Best Hits

KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to mmp:MMP0550)

Predicted SEED Role

"Glutamine ABC transporter, periplasmic glutamine-binding protein (TC 3.A.1.3.2)" (TC 3.A.1.3.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZS4 at UniProt or InterPro

Protein Sequence (264 amino acids)

>MMP_RS02910 ABC transporter substrate-binding protein (Methanococcus maripaludis S2)
MNNKVLILIIGLIGAVLAFSGCVSNSEAQSTEDNSWKNVEESGVLKVGLCAAWPPFESRN
EKTGEIEGFDVDLANALGEELGIEVEIVDAEWQALLGGLSKGDYDTLITCMSKKEASVEN
VEMSEVYYELNDVIVVRNDNNEINNVSDLSGKIVGVQLGSGSEQAVDALSGIKEIKRYNY
NPEAMIDLQNNRSDAVVVGYTYVLSEISKYPDLKVLDTPIASAEIVMVQKEGAKELTVKL
NEALSKIKENGKYDEIQDKWLSLE