Protein Info for MMP_RS02620 in Methanococcus maripaludis S2

Annotation: DEAD/DEAH box helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 759 PF04851: ResIII" amino acids 59 to 197 (139 residues), 39.8 bits, see alignment E=9.2e-14 PF00270: DEAD" amino acids 63 to 235 (173 residues), 116.9 bits, see alignment E=1.6e-37 PF00271: Helicase_C" amino acids 286 to 391 (106 residues), 60.3 bits, see alignment E=4.1e-20 PF09369: MZB" amino acids 651 to 729 (79 residues), 76.2 bits, see alignment E=5.2e-25

Best Hits

KEGG orthology group: K06877, (no description) (inferred from 100% identity to mmp:MMP0494)

Predicted SEED Role

"ATP-dependent RNA helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZX9 at UniProt or InterPro

Protein Sequence (759 amino acids)

>MMP_RS02620 DEAD/DEAH box helicase (Methanococcus maripaludis S2)
MVNLNNSKITNFLSKLSTDSVHKSNIELIKEIPPKNAEYNENNLDLPDNFEEYLLKKNKK
LYTHQYSALENVRIGKNILLTTSTASGKTLSFNLPILETLQNDKDATALYIYPTKALTND
QLNNLKNLENELNITLKPEIYDGDTPNSKRKSIREKSRIILTNPHELHQVLQYNPKWMSF
FKNLKYIVIDEAHTYRGIFGSNISFLIRRLRRICEDYGSYPQFILASATLANAKEFSEKL
VGLDFRVIDKDGSPKNKKYFVFYNTLKNEISESSWYSSAINILELCMKYGLQTIGFTLSR
KMAELITIWTKKSLGNNILSRKISSYRSGFTPEERRDIESRLKNGDLRAVTSTNALEVGI
DIGSLDSVIMYGYPGTLMSLWQQAGRAGRAGYDSVVTLLSRESPLDQYIIKHPETVFGKT
TENAVIDLENPQIIVGQLLCATAELPITLNDKPYFGENIEEYLNQLCDCGLLEKTDRGWV
YVNTVRAVELVSLDSIFSSEFKVVDEKGNLIEILDEMHAYPEAHVGAVLLHNSENYIIKE
MDLESKVCTAVKKDVEYYTKARGSTNVEIINELDRKDFGSVSIHFGEVIVSKTYIMYDVM
KFGKRMSQELLNLPPITFQTTALWYTFEDEFFNDFENLKEKDFGDGLHGTEHAMINIFPI
HIMCDSHDIGGLSTNMHYGTRKPSIFIYDGFEGGIGLSKKAYEMPEKIAKTALNLIKDCT
CEEGCPACLYSPNCGNDNQNLDKQYTLAILEKIVGIFEK