Protein Info for MMP_RS02530 in Methanococcus maripaludis S2

Annotation: type II toxin-antitoxin system mRNA interferase toxin RelE/StbE family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 PF05016: ParE_toxin" amino acids 11 to 89 (79 residues), 24.9 bits, see alignment E=1.3e-09 TIGR02385: addiction module toxin, RelE/StbE family" amino acids 11 to 89 (79 residues), 35.3 bits, see alignment E=6.5e-13

Best Hits

KEGG orthology group: None (inferred from 98% identity to mvn:Mevan_1655)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6LZZ7 at UniProt or InterPro

Protein Sequence (100 amino acids)

>MMP_RS02530 type II toxin-antitoxin system mRNA interferase toxin  RelE/StbE family (Methanococcus maripaludis S2)
MSDMKLAIRDKRVQKKLQKIFKKDKVHGDAIDSALDKILEYPNRGIPMTGELAGFRHLHV
YDSFVILYFVDEVNNVIYIDNYGHHDEMYSWNDKMKKSKK