Protein Info for MMP_RS02320 in Methanococcus maripaludis S2
Annotation: glutamate-cysteine ligase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to mmp:MMP0437)Predicted SEED Role
"Uncharacterized protein AF_2307"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6M035 at UniProt or InterPro
Protein Sequence (367 amino acids)
>MMP_RS02320 glutamate-cysteine ligase family protein (Methanococcus maripaludis S2) MIGTEHEYSINNPDLKAMPVSDLIIEEISGKIQNEFSFETVGISKELQKHVIEFKPLNPS ESISNLENQIFNGLKGFYEKTNNKYKLLGLGMHPTLNLSETSFWNHDEREVFDTYDRVFN LRQHGWMNIQALQVNVEYSTEEDLVRKHNKLRTLLPYLVAVTASSPIVEGNVTGYMDNRL LYYKKNQKEIPEICGNLIPEKLEKSSDYEKLLEKMYVELRKKDAEVLCEEWVNSRALIVR RERKCVEIKIMDEQESIYADMAVSAFINCLLRVNDLKVAEDDETILELTDIAIKSGKKKL KAELESLYKKAVSVATEEEKSYLIHIQNRIQNGNLSEVILKKYNSEKDISKILNEAESCL RENKTMF