Protein Info for MMP_RS02315 in Methanococcus maripaludis S2

Annotation: RimK family alpha-L-glutamate ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 PF02655: ATP-grasp_3" amino acids 89 to 263 (175 residues), 30.8 bits, see alignment E=4.6e-11 PF08443: RimK" amino acids 91 to 287 (197 residues), 50 bits, see alignment E=4.3e-17 PF07478: Dala_Dala_lig_C" amino acids 104 to 278 (175 residues), 40.3 bits, see alignment E=3.8e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0436)

Predicted SEED Role

"Ribosomal protein S6 glutaminyl transferase" in subsystem Ribosome biogenesis bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M036 at UniProt or InterPro

Protein Sequence (316 amino acids)

>MMP_RS02315 RimK family alpha-L-glutamate ligase (Methanococcus maripaludis S2)
MGKFGVFVDRQTLSSSNQLQSLIRFRDIAESMGHEFYFLFPNEIHKIKTLNGLFIRSKTD
PMNISYVASRIAELNGVKVIDDSKSIQICADKINMYLHMMKNNVPLPKTKFLRKSENNFE
NLKSIVEEIGLPLILKEPSTSFSMRVEKVNSLEEFSKVASRFLRLSDVLVAQEFIETRFD
WRVGILNGEVIYACKYLIPKDTFKIQDCVDGHRVYCMVESVMYDEVPKEVIKTALKAANA
VGTGLYGVDLKEKDGSIYVIEVNDNPSLETTEDEFYPEAYSKIVSYIMDDSRQKYSGGKM
KFSEVIDPDGVANDRN