Protein Info for MMP_RS02175 in Methanococcus maripaludis S2

Annotation: DUF1611 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 306 PF17396: DUF1611_N" amino acids 26 to 93 (68 residues), 42.5 bits, see alignment E=6.3e-15 PF07755: DUF1611" amino acids 109 to 290 (182 residues), 124.8 bits, see alignment E=3e-40

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0408)

Predicted SEED Role

"Protein often near L-alanine-DL-glutamate epimerase (cell wall recycling)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M063 at UniProt or InterPro

Protein Sequence (306 amino acids)

>MMP_RS02175 DUF1611 domain-containing protein (Methanococcus maripaludis S2)
MKRANLSHHDKVANGIRLFGNTLIDELNYDTFIWTKEILGPDDVKIWKETIEEEIKKGNN
IYNMARLCRVGENDYLKELASKYNVKYYDSSDPKKYDELRVFAKTGLEGINTKVMTIMGT
SRQSGKFTTCMILKKELEKRINIGIVGTEPQSLICGIDEMVVPQTIETCHCASTIFGAVK
KLDTKNRDLIIVSSQTGIFADTLEVGTGRGGGLISIAVLFGSKPDFTILASDSQDLEIIK
KNISAIELLSGKPVIAVTLNSRCMNEENLEESIEKMSKELAIPVVDVLKGINLDKLINEI
LLKLKN