Protein Info for MMP_RS01855 in Methanococcus maripaludis S2
Annotation: 2-hydroxyacyl-CoA dehydratase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 71% identical to Y007_METJA: Putative dehydratase subunit MJ0007 (MJ0007) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
KEGG orthology group: None (inferred from 100% identity to mmp:MMP0346)Predicted SEED Role
"2-hydroxyglutaryl-CoA dehydratase (Component D) related protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6M0C5 at UniProt or InterPro
Protein Sequence (373 amino acids)
>MMP_RS01855 2-hydroxyacyl-CoA dehydratase family protein (Methanococcus maripaludis S2) MEELKSIKKISEAFAGRKNELYGQKDEGRKVFGLFCTFVPTELILAANAVPVGLCGGKEG TIPSAEEILPRNICPLIKSSFGFKKDKACPYIEASDVIIGETTCDGKKKMFEHLAEMTRL HIMQLPHFRDDRSAKLWLAEVEELKKLIEEETGNKITEEKLKEAIDKVNNVRKLFYKIYE LRANNPSPINGKDSLKLFQLSYLLDINTIESVLEDLVEELEERVKKGEGYSGKRILIAGC PMVAGNTKIPELIEDTGAVVVGEESCTGTRQYENYVEGYTIEKLADRYFKIPCACKFSNE ERIERIKELVKEQNADGVVYYTLQYCHTFNVEGALIEKELKKAGIPIIRVETDYSESDKE QLKTRIEAFVEMI