Protein Info for MMP_RS01685 in Methanococcus maripaludis S2
Annotation: indolepyruvate oxidoreductase subunit beta
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00180, indolepyruvate ferredoxin oxidoreductase, beta subunit [EC: 1.2.7.8] (inferred from 100% identity to mmp:MMP0315)Predicted SEED Role
"Indolepyruvate oxidoreductase subunit IorB (EC 1.2.7.8)" in subsystem Aromatic amino acid interconversions with aryl acids (EC 1.2.7.8)
Isozymes
Compare fitness of predicted isozymes for: 1.2.7.8
Use Curated BLAST to search for 1.2.7.8
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6M0F6 at UniProt or InterPro
Protein Sequence (199 amino acids)
>MMP_RS01685 indolepyruvate oxidoreductase subunit beta (Methanococcus maripaludis S2) MNFSVIICGVGGQGVVLASRLLAITAMNSGFHVNTAETLGMSQREGSVVSHLQFGDFIKS SLIPEGGADLIIGLELSEVARNLHFLKKNGKIITNCKMILPSARSSNEKYDSEQIINFIN KYVKSTICIDFSKIAKIAGNPKSMNVSVLSAAFYTGFLPLEYNDFLKTIESEIPEKYRDI NLNAAKLSAETIMLEGNNE