Protein Info for MMP_RS01655 in Methanococcus maripaludis S2

Annotation: DsrE family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 114 PF02635: DsrE" amino acids 2 to 114 (113 residues), 98.2 bits, see alignment E=3.7e-32

Best Hits

Swiss-Prot: 75% identical to Y989_METJA: Uncharacterized protein MJ0989 (MJ0989) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K07235, tRNA 2-thiouridine synthesizing protein D [EC: 2.8.1.-] (inferred from 99% identity to mmp:MMP0309)

Predicted SEED Role

"Uncharacterized protein MJ0989"

Isozymes

Compare fitness of predicted isozymes for: 2.8.1.-

Use Curated BLAST to search for 2.8.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M0G2 at UniProt or InterPro

Protein Sequence (114 amino acids)

>MMP_RS01655 DsrE family protein (Methanococcus maripaludis S2)
LKFTVIIGDAPYGKERAYSALRFALTALLEGIDVNIFLLEDGVYVGKKDQNPAGVPKYSE
LLENAIEAGAVVKACGPCGKARGISEEELLDGIAFGTMHDLIAFVKEADKTINF