Protein Info for MMP_RS01455 in Methanococcus maripaludis S2

Annotation: nickel pincer cofactor biosynthesis protein LarC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 TIGR00299: TIGR00299 family protein" amino acids 4 to 390 (387 residues), 303.9 bits, see alignment E=8.9e-95 PF01969: Ni_insertion" amino acids 5 to 390 (386 residues), 357.2 bits, see alignment E=5.9e-111

Best Hits

KEGG orthology group: K09121, hypothetical protein (inferred from 100% identity to mmp:MMP0269)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M0K1 at UniProt or InterPro

Protein Sequence (404 amino acids)

>MMP_RS01455 nickel pincer cofactor biosynthesis protein LarC (Methanococcus maripaludis S2)
MTKVLVIDPKIAGMSGDMFVSSLLALTNSYDLMDELILELEKLNNCNSFKVSVMDEKVNG
ISAKQLKIEIDEERIKNPDELKEIIINTSKNLMSEKGVKICENIINDLIEAEKKLHGDHF
HLHEISSLDTVFDIVLPVLILEKNGFLDGKIYSTPPSLGNGRISMDHGIIPSPAPSTLEI
LCKHEIKCSKVDSEFELLTPTGAAILSNVTDEFTDSYPEIVLLKTAYGAGTKRMEHVPNV
LRLVEGKTDEKIIEKTVILETNIDDISSEILAYAVERLLNEGAPDVFITPVFGKKNRPSS
MISVICPYHVHEKFAKILIEETGTLGVRINHYDKIRAKRRMEKLTLDINGVNFGFDVKIS
DLNGEIVNIKPEFEDLKKIAKNLNIPLRDVLRHANNKIKEIYGF