Protein Info for MMP_RS00620 in Methanococcus maripaludis S2

Annotation: 4Fe-4S binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 205 PF00037: Fer4" amino acids 44 to 62 (19 residues), 23.5 bits, see alignment (E = 2.2e-08) amino acids 71 to 87 (17 residues), 22.4 bits, see alignment (E = 4.8e-08) amino acids 154 to 173 (20 residues), 22.2 bits, see alignment (E = 5.6e-08) PF12800: Fer4_4" amino acids 44 to 58 (15 residues), 13.2 bits, see alignment (E = 6e-05) amino acids 71 to 83 (13 residues), 12.8 bits, see alignment (E = 8.4e-05) amino acids 95 to 108 (14 residues), 11.9 bits, see alignment (E = 0.00016) amino acids 127 to 141 (15 residues), 11.3 bits, see alignment (E = 0.00026) amino acids 155 to 168 (14 residues), 13 bits, see alignment (E = 7.2e-05) PF12838: Fer4_7" amino acids 46 to 85 (40 residues), 27.5 bits, see alignment 2.2e-09 amino acids 156 to 204 (49 residues), 34.7 bits, see alignment E=1.2e-11 PF13237: Fer4_10" amino acids 69 to 108 (40 residues), 24.6 bits, see alignment 1.2e-08 amino acids 154 to 202 (49 residues), 32.6 bits, see alignment E=3.9e-11 PF12798: Fer4_3" amino acids 71 to 85 (15 residues), 19.8 bits, see alignment (E = 6.4e-07) amino acids 191 to 203 (13 residues), 13.9 bits, see alignment (E = 5.1e-05) PF13187: Fer4_9" amino acids 128 to 171 (44 residues), 29.2 bits, see alignment 4.5e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0104)

Predicted SEED Role

"Polyferredoxin MJ0934"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M114 at UniProt or InterPro

Protein Sequence (205 amino acids)

>MMP_RS00620 4Fe-4S binding protein (Methanococcus maripaludis S2)
MSHEGEEFNKIFSKGKFLKNIFFNLFRSYKNPEVIGETTNPELDDCICCGLCVDVCPTNA
ISVFKFRDIICEHCGACLNVCPVDAIEKNRFSVDPEKCIKCGVCSIFCTIPILKNEIPVL
NVPEVTTECNNCKLCIQKCPQKAISFEDGKISINSKCNLCLKCVEFCPLNALKSPKESLK
SKIIKVDLNSCIFCKDCEEICPVKK