Protein Info for MMP_RS00295 in Methanococcus maripaludis S2

Annotation: gamma carbonic anhydrase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 151 PF00132: Hexapep" amino acids 2 to 29 (28 residues), 27.1 bits, see alignment 2.4e-10 amino acids 57 to 87 (31 residues), 27.8 bits, see alignment 1.5e-10 amino acids 73 to 107 (35 residues), 42.2 bits, see alignment 4.2e-15 PF14602: Hexapep_2" amino acids 56 to 88 (33 residues), 19.9 bits, see alignment 5.2e-08 amino acids 75 to 106 (32 residues), 31.3 bits, see alignment 1.4e-11

Best Hits

Swiss-Prot: 67% identical to Y304_METJA: Uncharacterized protein MJ0304 (MJ0304) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0049)

Predicted SEED Role

"carbonic anhydrase (gamma family Zn(II)-dependent enzymes)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M168 at UniProt or InterPro

Protein Sequence (151 amino acids)

>MMP_RS00295 gamma carbonic anhydrase family protein (Methanococcus maripaludis S2)
MAKIAKNAVVIGDVELGENVNIWYGAVLRADINKIKIDDDSNVQDNCTVHCSKDYPVFIG
KGVSVGHGAVIHGCTIEDNVLIGMNSTVLNGAKIGKNSIIGANALVSQNKEIPPNSMVLG
VPGKVVRTLTDDEVNSIKENAKNYLELSKNL