Protein Info for MMP_RS00285 in Methanococcus maripaludis S2

Annotation: TIGR04013 family B12-binding domain/radical SAM domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 TIGR04013: B12-binding domain/radical SAM domain protein, MJ_1487 family" amino acids 3 to 360 (358 residues), 475.5 bits, see alignment E=5.5e-147 PF02310: B12-binding" amino acids 39 to 104 (66 residues), 38.9 bits, see alignment E=7.4e-14 PF04055: Radical_SAM" amino acids 138 to 307 (170 residues), 92.4 bits, see alignment E=3.7e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0047)

Predicted SEED Role

"Uncharacterized protein MJ1487"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M170 at UniProt or InterPro

Protein Sequence (369 amino acids)

>MMP_RS00285 TIGR04013 family B12-binding domain/radical SAM domain-containing protein (Methanococcus maripaludis S2)
MIGFRMTSKNKYSVSKLYPLIGGTLFKEFGEIIENLDSLDILIYSFMSMQEKEVLSEINE
LKKLKKDVILIAGGAHPSGCPEDTLNLGFDHVIVGEGEISLPNLINSIKSGKTPEKIIKG
KPIENFDDYEKIWPLAPIEITRGCPYNCRFCQTPQIFGKNIRHRSIESIVKIVKTMGDIR
FVTPNAFSYGSKTGTKPDIEKLEKLMKSLFEIKKRLFFGTFPSEVRPEFVNFETLDLVNK
YCDNRYIHFGAQSGSDEVLKHIRRGHLVSDVINAVETSKECDLIPKVDFIFGFPDETDDQ
RKESIDLMKYIIKKNGKVHAHYFMPLCGTYFENSTPELLEKETLDILGKMAKKGQITGSW
GYQYSKNLE