Protein Info for MMP_RS00250 in Methanococcus maripaludis S2
Annotation: Flp pilus assembly complex ATPase component TadA
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02283, pilus assembly protein CpaF (inferred from 100% identity to mmp:MMP0040)Predicted SEED Role
"secretory protein kinase @ intein-containing"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (archaea)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q6M177 at UniProt or InterPro
Protein Sequence (549 amino acids)
>MMP_RS00250 Flp pilus assembly complex ATPase component TadA (Methanococcus maripaludis S2) MGLFDRIQSRDSNPSVAKKNNVSEKVSETPSILDNSEKVKKPEIKVGFSVNERAKQPVEE FERDSTSSILDKYFVKVDDIDFDVIIEKENGVTLYKIPEITLMNTALAKFSDMDIKTIKA ELSESTLQKLGQIQGYLKNYSEKNNLHLRDIEILHLSHYFYLIIGKLGLLEIPLNDSKLE EVMVNGVESPSFVFHRKYQMCETNIRLDRHEATRVVESIAYLAGRTIDSRTPMLDAFLPD GSRVNATMSDVTLGGNTITIRKFSEDPLTIVDLINFGTFDLELAAFLWQAVEGYFGAKPA NTLIVGGTGSGKTTTLNVVSMFSMYTDRLVTIEDTPELQVPLTHLIKMITRPGRPGIQGY EITMDDLIKNSLRMRPDRIFVGEVRGSEAHSLLVAMNTGHDGCSGTLHANSADEALIRLI NPPMNVPKVMMSSVDFIINQQRIKRNKKTVRRILGVVEIGGSGENITKTELFKYDGISDS VVKTGICMWEEDVCQIAGITRDELMDDRINRKKVLKYMVNNNINDIRKVGDVLKQYQENP ENVLKNILE