Protein Info for MMP_RS00055 in Methanococcus maripaludis S2

Annotation: DUF2254 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 64 to 81 (18 residues), see Phobius details amino acids 98 to 120 (23 residues), see Phobius details amino acids 133 to 156 (24 residues), see Phobius details PF10011: DUF2254" amino acids 21 to 187 (167 residues), 38.6 bits, see alignment E=3.1e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to mmp:MMP0005)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q6M1B1 at UniProt or InterPro

Protein Sequence (527 amino acids)

>MMP_RS00055 DUF2254 domain-containing protein (Methanococcus maripaludis S2)
MLSKICKNCAYVMDYFLSKEWFQVLIIAAISAVLAYYSLFYFAWGTGFDENLRYILSTLP
QTQGAIVGIVASISIVAIQMVSQQYSTRITHLLLNKTFWGFIIAYIVSMSYEVLILGFMP
TARIPVFIGGYEISYHILIGILFFFVYFDFLILLPYMKNTINGLKPENVIDALINSISKD
EIKNYRSLDSENKDYKSARKIPKNTLRTVYYIIGKSLKSDHYMTARNGIILLGANYSVLA
KKGKFKNKKFFESYIDNLKNLGLTAYGTSFSISREAIISLEKISKFELNRNYDLSLRALR
GIKKIGLLYAQEYELKIDKSDEKELIHIVFEKLGNIIKFILSKPKHNEKITSKQVTFKIM
MFSEILKIFELILDKLNSREILKNEAAGTLILDALNNFSKPAIEFIKTNENSEFLSEITI
QTSETLKNFVKLISKTNEENESLNEYLTEILKIYGIILDLICEKTTEKTIDTILSDISEI
WKISNGKFEQIFGIGDIVENIDNSEKIKCADSLREQLLEKISKQDNN