Protein Info for MMJJ_RS07910 in Methanococcus maripaludis JJ

Annotation: CBS domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF00571: CBS" amino acids 10 to 59 (50 residues), 28.5 bits, see alignment 7.8e-11 amino acids 84 to 139 (56 residues), 37.8 bits, see alignment E=1e-13 amino acids 148 to 200 (53 residues), 56 bits, see alignment E=2e-19 amino acids 223 to 276 (54 residues), 53 bits, see alignment E=1.8e-18

Best Hits

Swiss-Prot: 55% identical to Y1225_METJA: Uncharacterized protein MJ1225 (MJ1225) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: None (inferred from 95% identity to mmq:MmarC5_0339)

Predicted SEED Role

"CBS domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (279 amino acids)

>MMJJ_RS07910 CBS domain-containing protein (Methanococcus maripaludis JJ)
MKIKTIVGEKKVEKVYPTTKIIEALTMMDKENVRRICVADPGTGRVEGILTNMDIVDFLG
GGSKYNLVKFKHNHNMLSAINEPVKEIMTDNVVLIKENAELNEVIDLYVEKKIGGMPVID
KSGVLITTINERDVIKYLKDQVDEKLLVKDCMTENVVSATPGERLKDVARTMLRNGFRRL
PVVSEEKLVGIITSTDFVKLFGSDWAFNHMKTGNIREITNVRIQDIMKTDIVSVTSDIKL
IDAIKKMNELNIGVLPVVDGEKLIGLITEKDIVKCIYKK