Protein Info for MMJJ_RS07745 in Methanococcus maripaludis JJ

Annotation: DUF5814 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 811 PF00270: DEAD" amino acids 207 to 372 (166 residues), 96.1 bits, see alignment E=4e-31 PF04851: ResIII" amino acids 218 to 367 (150 residues), 44.2 bits, see alignment E=4.1e-15 PF00271: Helicase_C" amino acids 421 to 524 (104 residues), 61.7 bits, see alignment E=1.6e-20 PF19131: DUF5814" amino acids 667 to 805 (139 residues), 101.4 bits, see alignment E=7.3e-33

Best Hits

KEGG orthology group: K03725, archaea-specific helicase [EC: 3.6.1.-] (inferred from 99% identity to mmp:MMP1284)

Predicted SEED Role

"Archaea-specific Superfamily II helicase MJ1401"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-

Use Curated BLAST to search for 3.6.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (811 amino acids)

>MMJJ_RS07745 DUF5814 domain-containing protein (Methanococcus maripaludis JJ)
MIIVRKLKKKKEEIQFIDLTDEKTYYGIIRPANNRITLYKCREEKAGNVNPIQPSKLINF
VRSNKVLLSGDEESLKLEEFLKQNNIKHGYIDLCPFCIIKGKFSEITDKYKIYNSEICLE
CAIDEVKHEVNINEEFIEKLLRRFKDANKVIELFKSKNPLKNPELTKYDVLTGNVDDNIK
NYEINELDIPDFLKEIIKNRGIDELLPVQTLSVKAGLLKNDNLLITSATSSGKTLIGELA
GIKNISEKKGKFLFLVPLVALANQKYVEFKDRYEKEGYSVSLRVGTGRLSENKGSGINSS
LDSDIIIGTYEGIDYLIRSGKLKDVGTVVIDEVHSMNMDERGARLDGLIGRLRYLFTCQM
IYLSATVGNPEELASKLGSKLVLYNGRPVPLERHLIFTKNDYGKLNLVKDIVKQEFSSKS
KYGFRGQSLIFTFSRKRAEYISNYLNTKGIKSDYYHGGMEYSKRRNVEDNFLKQKTMCVV
TTAALAAGVDFAASTVVLESLAMGGDWLNPSEFQQMCGRAGRKGMHDKGKVYSLVEIGKK
YHAKMENSEDEVSFKLLNSEPEEVSLEYSEDEEFEQVLANVCSIKNYKNKVTIPDVSKVP
VLGKNLGLNYVLESLSGYQMLDLQNKNINTTRYGYATSISFLYPKDAEKIRKNLHKNPLD
IVVSISPFENAYIPANLKNKISKTTNVNIPTRFTDAFEVIKENFEKIKDKTLRDEILPWL
IEFDGLIEEDIINYNSKKVLNLRINKKTPLQISKIIHDTLKLQTYSGDIYSYLETSINTL
DAVERIGNIYNKKIAKESEKLKKKMENPYKN