Protein Info for MMJJ_RS07435 in Methanococcus maripaludis JJ

Annotation: SMC family ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 993 PF13175: AAA_15" amino acids 1 to 282 (282 residues), 39.2 bits, see alignment E=1.1e-13 PF13555: AAA_29" amino acids 5 to 54 (50 residues), 27.4 bits, see alignment 3.3e-10 PF13476: AAA_23" amino acids 6 to 218 (213 residues), 39.3 bits, see alignment E=1.7e-13

Best Hits

Swiss-Prot: 94% identical to RAD50_METMP: DNA double-strand break repair Rad50 ATPase (rad50) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K03546, exonuclease SbcC (inferred from 94% identity to mmp:MMP1341)

Predicted SEED Role

"DNA double-strand break repair Rad50 ATPase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (993 amino acids)

>MMJJ_RS07435 SMC family ATPase (Methanococcus maripaludis JJ)
MIIKNIKMENFRSHRNTSINFNKGITSIIGQNGSGKSSIFQAMNFALFAPRGNNFRIENL
MQQGSASFSVELEFEMMGNTYLVKRKRFQNKTDDKLYVNGKLNAESASEINKKMEEILEI
DNSVFSNAIYIKQGEIANLIQMTPRDRKEVIGKLLGIEKYEKASEKMNIVKKSYEETLLK
LEGELTQEPEILENLEKLKIEVSESEILKEEILKKYGNLEKLKLEKNSELTHMEEKFAEN
NRLKENLKDVISEIKNINLEIQNFKNSLSLVVEESKNISKNEENYKKYLELELNIKELKN
KLINHKSNYESYNKLKTIEESLIKELNNLEESLKDNKKNPDELKENLKENEEKILILDKI
KEKIKELEFIEKQIYEIKIHKKTVETLFDSVKIYDDSIKTFEELKTKKNSYENLLKEKND
LEKKFQNETDEKTKLISELTDLKKIEEKINLEIEFKEKYEDLSEKIDKLNEIVLKKESKI
SETKNSKAELEKTKDSCHVCQSKISEEKKQELLEKYNSEIENEKLSTESLKKQLEIILNK
KEHIKVKLNEIDSFKLKYGELKEKKNYSLKVEESIIETTEKLNELIGKINEYSSLNDEIS
LIENKLKDLEKDYKNYNYSAQFLTKNEESEILNKKLELSKIIGDYDSSKIENEKKSLENL
KDELKNIIYNLEREINLKTELKNIQNDISSKIGIVECYVKWEAEKSDFENKLSECKKSYE
KYMESLAVLKNYSKTYSVEINNLNEFLNQKIAEKEHFCEKLLETRLTIEKNIQSVNYNPE
MHENAKKVYENIFNEFNDISRTLERITSELKLKNENIIYLNEKIQNLSNKKEERRKIEEF
KEYLDKIKREIFSKDGFQKYLREKYIPLIQRHTNQIFQEFELPYSHIQLKDDYSLIVDGL
PVETLSGGEQIAVSLALRLGISKAVCNNIECIILDEPTAYLDEDRRKNLLNIFKNIKTIN
QMAIITHHQELEQIADNIVKVRKIGENSKISLE