Protein Info for MMJJ_RS07165 in Methanococcus maripaludis JJ

Annotation: chromosome segregation protein SMC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1189 PF02463: SMC_N" amino acids 4 to 1182 (1179 residues), 182.8 bits, see alignment E=1.7e-57 TIGR02168: chromosome segregation protein SMC" amino acids 4 to 1188 (1185 residues), 594.5 bits, see alignment E=4.2e-182 TIGR02169: chromosome segregation protein SMC" amino acids 5 to 1188 (1184 residues), 802.7 bits, see alignment E=5.5e-245 PF13476: AAA_23" amino acids 6 to 267 (262 residues), 44.5 bits, see alignment E=7.4e-15 PF06470: SMC_hinge" amino acids 539 to 651 (113 residues), 110.5 bits, see alignment E=1.6e-35 PF13304: AAA_21" amino acids 945 to 1161 (217 residues), 36.8 bits, see alignment E=1.1e-12

Best Hits

Swiss-Prot: 64% identical to SMC_METVO: Chromosome partition protein Smc (smc) from Methanococcus voltae

KEGG orthology group: K03529, chromosome segregation protein (inferred from 99% identity to mmp:MMP1397)

Predicted SEED Role

"Chromosome partition protein smc" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1189 amino acids)

>MMJJ_RS07165 chromosome segregation protein SMC (Methanococcus maripaludis JJ)
MASLSEIHMKNFKSFKNSKLKIPDGFTAILGPNGSGKSNTIDGICFVLGKTSAKSLRAGK
FNQLITYHNGKRENFAEVTLIFDNKDRKMPVDSDKVGISRKVKINGDNNYYLIWNEEKEV
KENGEIKTVKEEKRKKVKKSEILDVIGKISLSADGFNIILQGDLIKIIDTTPNERRKIID
EISGVAEFDEKGEKAKKELEKAREFIEKIDIRINEVKNNLEKLKKEKEDAETHVKLTEEL
KATKYILTSKKIEFLNGILEKTKEEIEALKEMKVCFLKEISEYDAKSNDIRNRLQNLINE
LNEKGNEEIMELHKSIKEMEVTVDNDKKSLNGALDDLKNVNSQSEKKGQDLVETRQKIET
IRTETLQKEAEINTLKTEMENLETEKKKLKSKVEESETQTEILKQQERKLSERINESQNE
LYNFKNEFNALENEINKKSFNLTKNKETIETLQKELEEIRSEHEDTKSLYKELEDVAVEL
EYSKKKVVTLLENKKEYQEKLDKSHADYIKENAKIKAMKDMEDFSLDRAVKSVLEAKLPG
VVDIAGNLGKTDAEYKTAIENAGGNRLNYIVVKRMDDGARAIQYLKKNNLGRTTFLPLDR
INGPEALYLYDEGIVGRAIDLVEFKPEYENLFRYVFGNTIIVENLDYAKTLSKDHKARFV
TLEGEVIEPSGAMIGGRSRKKSVIKVDIDTSKLEKLAEQISELDGTLSETKDEIERLQNK
NATYSTRKMELESRLKIIKDLEHKKEGILTNNGVKIKELELESRKLEEELDYLEGSKEEL
ERKIEEFTKKISGFTTQRERISEEIASFENSEHSKRIKVIDETILNFEKKKNEFENEIKR
DAVLIKEVLIPKISELNSNIKELSEKKTILEQNIQFYKNNVEKNFEILKTKKERYEDLTK
DLRELTEKKEAFEKELEILNGEKRRVYGRINQNESQINSLSIDKAKYETRLEEEDRKLYV
CENIEQISEDITSKIKEFDVDALESHQIDLEGHIKKLEPVNMRAIDDYQYIVDRYDELFE
KRTDYENEEKKYLHLIEEVSKRKKEVFMDVYLKVAENYEKIYTEIGGSGKLSLENPEDPF
SGGLLIDASPMNKKLQSLDVMSGGEKSLTALAFLFAIQHLNPAPFYVLDEVDAALDTKNA
GLIGEMIKNASKDSQFIVISHREQMISKSDVMYGVCMENGLSKLVGLKI