Protein Info for MMJJ_RS06440 in Methanococcus maripaludis JJ

Annotation: DUF4870 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 105 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 41 to 60 (20 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details PF09685: DUF4870" amino acids 13 to 97 (85 residues), 36.7 bits, see alignment E=1.8e-13

Best Hits

Swiss-Prot: 49% identical to Y105_ARCFU: UPF0132 membrane protein AF_0105 (AF_0105) from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

KEGG orthology group: None (inferred from 99% identity to mmp:MMP1541)

Predicted SEED Role

"UPF0132 membrane protein MJ1527"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (105 amino acids)

>MMJJ_RS06440 DUF4870 domain-containing protein (Methanococcus maripaludis JJ)
MALFGLKDTHTALLAYLLGFVSGIIVLLLEKESSFVKFHAMQSTIAFGAIFILNIISGYI
PIVGGILGNLLSLIGLIIWIVGMIKAYQGERYKFPIIGDIAEKQI