Protein Info for MMJJ_RS06105 in Methanococcus maripaludis JJ

Annotation: DUF99 family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 183 PF01949: DUF99" amino acids 6 to 179 (174 residues), 200.9 bits, see alignment E=5.9e-64

Best Hits

Swiss-Prot: 60% identical to Y1150_METJA: UPF0215 protein MJ1150 (MJ1150) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K09120, hypothetical protein (inferred from 95% identity to mmx:MmarC6_1063)

Predicted SEED Role

"Protein of unknown function DUF99"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (183 amino acids)

>MMJJ_RS06105 DUF99 family protein (Methanococcus maripaludis JJ)
MEYKDEIGVIGIDDAPFNKSDKEALIIGTYMRGNKIVDEILFKKIEKDGFDSTEHILKIV
KDKHFTKINAIFLDGVTFGGFNIADIVKIYNETKIPVIAVMEKEPDLLKMKSALKKYFFD
FPEKIEMLESFPKPEPFENIFIQCIGISFEDACKVIKKTRLRSKIPECLRISHIVGRGFL
NID