Protein Info for MMJJ_RS04520 in Methanococcus maripaludis JJ

Annotation: coenzyme F430 synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 PF27274: CfbE_C" amino acids 293 to 378 (86 residues), 34.5 bits, see alignment E=2.1e-12

Best Hits

KEGG orthology group: None (inferred from 93% identity to mmp:MMP0173)

Predicted SEED Role

"methanogen enzyme similar to murein synthesis amino acid ligase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (400 amino acids)

>MMJJ_RS04520 coenzyme F430 synthase (Methanococcus maripaludis JJ)
MLIIDINHGALDLAVEYKKSGKVPVIWDIYGKVERDKNFKEENKNILSKFKIISKKETPN
FLKYNEVIAPVHCPIDVKFKTFHEAVSEIISKKYPKTVEKMITVTGVKGKTTTTELLKHI
LSEKYSVFCHNSSDGSITPVNVLNILNKLNEEKKLQIYDFLIFEISLGIVSSNYSILTNI
LENYSIAGGRRQASIKIDSLKNSKIVFVNEDLKNRFEICHKNLNVVKNAKIISKYPLKFN
YSKNDFEFNESVFGSHFIENSIFAIELCSYFMGFEEIKNSLKSFEIKNRMNVEKKNNYQI
VKNINPGLDLKAIDYAIFDFLNLFETGTIIVGGDIGCTCEEINIKKLADLIKKYNKKGVK
FLLSGSVGKNLKEIINLEFVDINNYAVEENTLVIYRSKLC