Protein Info for MMJJ_RS02090 in Methanococcus maripaludis JJ

Annotation: tyramine--L-glutamate ligase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 302 PF18301: preATP-grasp_3" amino acids 60 to 118 (59 residues), 37.2 bits, see alignment E=2.6e-13 PF02655: ATP-grasp_3" amino acids 123 to 259 (137 residues), 151.4 bits, see alignment E=2.4e-48

Best Hits

KEGG orthology group: K06914, (no description) (inferred from 98% identity to mmp:MMP0564)

Predicted SEED Role

"COG1821 family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (302 amino acids)

>MMJJ_RS02090 tyramine--L-glutamate ligase (Methanococcus maripaludis JJ)
MNNKKIFLFEFTVGTGLVPDELLAEGKLMFDILLNQFLDEKYTVKTVLCEKIAKKYPKYN
EINNLEIIVSNNYINSFKEGLNDSDFALAIAPEEDLILYNLTELIEESGCLNLGCEKSGV
KIAGDKFLTYEAIKNAVNTPKTFPVKKYVIKNRLGCDSTHDTFDENYIVQEFIEGEPYSV
IFIAKNKKFYPVCMNKQYIEERYCGGEINIEHTLKEKAIIECKKTLKKIEGINGYVGVDL
MIKGEEISILEVNPRITTSICGIKSKPSIGKLLIDNALEKDIKFEVESCLKFKRNDFGFE
FL