Protein Info for MMJJ_RS01625 in Methanococcus maripaludis JJ

Annotation: bile acid:sodium symporter family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 transmembrane" amino acids 21 to 38 (18 residues), see Phobius details amino acids 44 to 64 (21 residues), see Phobius details amino acids 76 to 100 (25 residues), see Phobius details amino acids 106 to 128 (23 residues), see Phobius details amino acids 135 to 159 (25 residues), see Phobius details amino acids 166 to 189 (24 residues), see Phobius details amino acids 201 to 220 (20 residues), see Phobius details amino acids 227 to 251 (25 residues), see Phobius details amino acids 265 to 285 (21 residues), see Phobius details amino acids 289 to 311 (23 residues), see Phobius details PF13593: SBF_like" amino acids 48 to 312 (265 residues), 73.4 bits, see alignment E=3.1e-24 PF01758: SBF" amino acids 50 to 228 (179 residues), 153.3 bits, see alignment E=9.6e-49 PF03547: Mem_trans" amino acids 51 to 154 (104 residues), 32.2 bits, see alignment E=7e-12

Best Hits

Swiss-Prot: 52% identical to YOCS_BACSU: Uncharacterized sodium-dependent transporter YocS (yocS) from Bacillus subtilis (strain 168)

KEGG orthology group: K03453, bile acid:Na+ symporter, BASS family (inferred from 98% identity to mmp:MMP0653)

Predicted SEED Role

"Sodium-dependent transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>MMJJ_RS01625 bile acid:sodium symporter family protein (Methanococcus maripaludis JJ)
MDRGAIQLKKTLWKLTKFSEDYFALLVILGSIIGFFNPSIFGWAIPHISLFLGIIMFGMG
MTLNKDDFKTVLERPIDVVFGSILQFSLMPLLAFLVITIFHLPTELALGFILLGSCPGGT
ASNVITYLAKGDVALSVAITTFSTLLAPMITPILVLWFAGTWIDVSAYSMFLSIVKIVLI
PVILGVIINNSLGKKIDSIRHVLPLLSVVAIVLIVGAIIGVNSEKIVSSGVIVLLAVIIH
NAFGLLFGYIGTKIIGMDEKKSRAVTIEVGVQNSGLAVALATIHFSPLAAVPGAIFSVWH
NITGPILANYWSKKDKKESFV