Protein Info for MMJJ_RS00685 in Methanococcus maripaludis JJ

Annotation: nitrogenase molybdenum-iron protein subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 PF00148: Oxidored_nitro" amino acids 21 to 448 (428 residues), 407 bits, see alignment E=4.2e-126

Best Hits

Swiss-Prot: 99% identical to NIFK_METMP: Nitrogenase molybdenum-iron protein beta chain (nifK) from Methanococcus maripaludis (strain S2 / LL)

KEGG orthology group: K02591, nitrogenase molybdenum-iron protein beta chain [EC: 1.18.6.1] (inferred from 99% identity to mmp:MMP0857)

MetaCyc: 43% identical to [FeV]-nitrogenase complex dinitrogenase component beta subunit (Trichormus variabilis)

Predicted SEED Role

"Nitrogenase (molybdenum-iron) beta chain (EC 1.18.6.1)" in subsystem Nitrogen fixation (EC 1.18.6.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.18.6.1

Use Curated BLAST to search for 1.18.6.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (462 amino acids)

>MMJJ_RS00685 nitrogenase molybdenum-iron protein subunit beta (Methanococcus maripaludis JJ)
MSELNVIKKERTAVINPIVTCQPLGAMYAVSGIERGMPLVHGSQGCSTFVRYGFARHFRE
PADIAVTSLHEDAAVFGGRKNLISGLGNLAARFKPDVMGVVTTCSSEIIGDDVAGFIKTA
KVEIAKKMGEEAASKIKIVQINTPSFVEHQFKGYDNAIKAIVDTLAEPKDEENGKLNIIP
GIVNPGDIREIKHMLSLMGVEGILLTDTSDPFDSPLRPSKADKNPYYQKGGTPLADIQDC
ANSLGTISLANYASSAPASLEKKYNMPSKVSEAPIGIQNTDSFIRTVKKFTGNDVTDEIL
DERGIVIDAMADVASRYLFGRKVAIYGDPSITVGMARFVAELGMIPKVVCTGVKNEYFVN
DLKKVAKESDEDIDALFGQDLRALDVYLKENPVDLMIGSSDGRLMAKDLGIPLYRVGYPV
YDRVGYQRRPIIGYNGALNLVDGITNTILDKYYETQDWKLQQ