Protein Info for MMJJ_RS00585 in Methanococcus maripaludis JJ

Annotation: S-layer protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 548 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR01564: S-layer protein" amino acids 6 to 548 (543 residues), 460.2 bits, see alignment E=5.5e-142 PF05124: S_layer_C" amino acids 34 to 548 (515 residues), 214.1 bits, see alignment E=1.2e-67 PF05123: S_layer_N" amino acids 120 to 453 (334 residues), 320.5 bits, see alignment E=1.7e-99

Best Hits

Predicted SEED Role

"S layer protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (548 amino acids)

>MMJJ_RS00585 S-layer protein (Methanococcus maripaludis JJ)
MAISIKKIVSIGLGGLMLGTTLSSSAFAVEQVGDVDSFVSDIVSGNNSNIDIIVGSNSVA
SDVVSAANIAAKIGSLSFLEQHDESASATLSVSASASSDDFDLLNDDAADDSINFTSNGN
GLFIACADDDYADVLADITYDDSTGLDADNGAKSLGKLSTLSSVDDIDPSDWFNSDDDAY
EFLFAKLNNDSGEWNINEEGLAYAVISFKDDASSFDDITTLCPGKRIPFMGEEWVIIGMS
ADKDSFALGKEVYDGVIKEGESYTLGNGYEVKILNIIQSLDDENECKVNAQLLKDGKVIT
EVFDNPRLNMCSNGIGVRINSAWQNIGSDYGYAELVIVNNMKCLSLGEEYIPDWETYGIL
KGNNTLEYTDDFKSFEYGQKKVGLALKYVGDDLEDIGSGDEITIANYGTFTLDDEDEDDK
LSVFFEMNEEKEVSIVKNQKVNVLNAEIVADAIFAGDEESLTVNAPVVKLDTETSMESSE
NPLILVGGPFVNSITKELADTRLIAINDDSLATLSVVSETANGNDVLVVAGGDRIATTEA
ANALIAMI