Protein Info for MMJJ_RS00480 in Methanococcus maripaludis JJ

Annotation: flippase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 transmembrane" amino acids 22 to 47 (26 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 86 to 108 (23 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 154 to 197 (44 residues), see Phobius details amino acids 225 to 242 (18 residues), see Phobius details amino acids 262 to 285 (24 residues), see Phobius details amino acids 299 to 318 (20 residues), see Phobius details amino acids 334 to 353 (20 residues), see Phobius details amino acids 365 to 384 (20 residues), see Phobius details amino acids 390 to 413 (24 residues), see Phobius details PF01943: Polysacc_synt" amino acids 10 to 290 (281 residues), 93.3 bits, see alignment E=3.8e-30 PF03023: MurJ" amino acids 90 to 417 (328 residues), 32.3 bits, see alignment E=8.6e-12 PF01554: MatE" amino acids 231 to 383 (153 residues), 37.2 bits, see alignment E=5e-13 PF14667: Polysacc_synt_C" amino acids 337 to 411 (75 residues), 67 bits, see alignment E=4.2e-22

Best Hits

KEGG orthology group: None (inferred from 96% identity to mmp:MMP0896)

Predicted SEED Role

"Membrane protein involved in the export of O-antigen, teichoic acid lipoteichoic acids"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>MMJJ_RS00480 flippase (Methanococcus maripaludis JJ)
MIKNLKKDGILKDSAYMIFSNMYSKFAAYLFYFLIPFILGTEGFGVIKGLMPILDTLVII
FCSGIPPAMAKFISGGDFNENTWIYDILKVMFIFSIFGAIFTVFLKYLLGGNYSNLPDVY
FYAVAVALPFSVVISWSRGVLQGNLKIKNLSKTWILENTSKVVFLVILSYLFGVVGGILS
ISVSFLLGGIFGIYLLSKSNLKYSFSNILKNIFSPIKEKESVKKVIYYSIPIALTTASYR
LINDLDGIFILSMLGAYDNGVYGYASLLSRLLFLFASAIAIVLIPRISKSKDISYFKKAT
ILNISIVLPALLVIFLFSKELLNLFFGISTPESIASLKILSVSAVFMSTYTICASSLQGL
GYAKIPVYVLFLGILLNAVFNYTLIPHMGIIGGAIATLSSSFVVFVLIWIITFTKLKKIK
NNS