Protein Info for MMJJ_RS00235 in Methanococcus maripaludis JJ

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 613 PF02730: AFOR_N" amino acids 24 to 201 (178 residues), 69.9 bits, see alignment E=2.5e-23 PF01314: AFOR_C" amino acids 236 to 540 (305 residues), 72.5 bits, see alignment E=3.7e-24

Best Hits

Swiss-Prot: 57% identical to Y1185_METJA: Uncharacterized protein MJ1185 (MJ1185) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)

KEGG orthology group: K11389, glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) [EC: 1.2.7.6] (inferred from 97% identity to mmp:MMP0945)

Predicted SEED Role

"Glyceraldehyde-3-phosphate: ferredoxin oxidoreductase (EC 1.2.7.6)" in subsystem Glycolysis and Gluconeogenesis, including Archaeal enzymes (EC 1.2.7.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.7.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (archaea)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (613 amino acids)

>MMJJ_RS00235 hypothetical protein (Methanococcus maripaludis JJ)
MNILIDGSRQNYEEIEGSEFPISFGINLHNMQETWKYDAFDEKNIFCFGKGVLPIIGGHR
LIFSFRSPLWDGFHFSAMGGAGYTFKDTGIQNVAITGKCEVPTVIVLNGEEDKLKIEFMP
FTEEITDIYEFNDKIIDLFKEKNYRAFLVGPASKTTNMGGIYSQTIRNGKIVEGSEDWAA
RGGGGSVLYQAHNVLGVVFFGKKTPEKNLKEIVEEHYNKPYTKVVLEHTEKYRYSEEKKT
GGTFGNNYHVTMELTPVFNWRMPFIDKNKRMKLHKKIIEYFVNRFDKEAIETKNWTNCGE
PCPVVCKKYRKGLHVDYEPYEANGPCIGVFDIYAADKVVHTVDKLGFDAIEFGNLCSWTF
ELLNNGMLKPEEVGIEKPVFDISNFEEDDDILKNSMHNAQQAVKLAEIIAFQTNEFGKIC
KSGTRRAGKILDEKYPDRVNDKKFEDFGVYDSFGEQGQISPTMYWAIGNFMPYLIQGKYL
THYQCGVFLEPEELAELSVKNSIEEITLENLGICRFHRKWITPIIDKLVKEVSDVNLNEE
SMELFKKIAKYDSNIGCPEMESERVKELIIAGAFEFENEKWSKEFENGNFNEYIKRVLEK
YSELLEIDWKLKE