Protein Info for LRK55_RS18160 in Rhodanobacter denitrificans MT42

Annotation: peptide-methionine (S)-S-oxide reductase MsrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 169 TIGR00401: peptide-methionine (S)-S-oxide reductase" amino acids 4 to 152 (149 residues), 169.1 bits, see alignment E=4.6e-54 PF01625: PMSR" amino acids 6 to 152 (147 residues), 193 bits, see alignment E=1.8e-61

Best Hits

Swiss-Prot: 81% identical to MSRA_MYCMM: Peptide methionine sulfoxide reductase MsrA (msrA) from Mycobacterium marinum (strain ATCC BAA-535 / M)

KEGG orthology group: K07304, peptide-methionine (S)-S-oxide reductase [EC: 1.8.4.11] (inferred from 86% identity to mci:Mesci_2981)

Predicted SEED Role

"Peptide methionine sulfoxide reductase MsrA (EC 1.8.4.11)" (EC 1.8.4.11)

Isozymes

Compare fitness of predicted isozymes for: 1.8.4.11

Use Curated BLAST to search for 1.8.4.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (169 amino acids)

>LRK55_RS18160 peptide-methionine (S)-S-oxide reductase MsrA (Rhodanobacter denitrificans MT42)
MSTERAILAGGCFWGMQDLIRRQDGVVSTRVGYSGGDVPNATYRNHGSHAEAIEIVFDPA
RIGYRALLEFFFQIHDPSTPNRQGNDRGSSYRSAIFYTSEEQRRIAEDTIADVDASGLWP
DKVVTEVAPAGDFWEAEPEHQDYLERYPDGYTCHFIRPGWKLPRRQKAG