Protein Info for LRK55_RS17745 in Rhodanobacter denitrificans MT42

Annotation: Rne/Rng family ribonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1050 TIGR00757: ribonuclease, Rne/Rng family" amino acids 13 to 420 (408 residues), 530.2 bits, see alignment E=1.8e-163 PF00575: S1" amino acids 36 to 116 (81 residues), 39.5 bits, see alignment 9.1e-14 PF10150: RNase_E_G" amino acids 120 to 389 (270 residues), 340 bits, see alignment E=1.6e-105 PF20833: RNase_E_G_Thio" amino acids 401 to 486 (86 residues), 108.2 bits, see alignment E=2.7e-35

Best Hits

Predicted SEED Role

"Ribonuclease E (EC 3.1.26.12)" in subsystem RNA processing and degradation, bacterial or Ribosome biogenesis bacterial (EC 3.1.26.12)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1050 amino acids)

>LRK55_RS17745 Rne/Rng family ribonuclease (Rhodanobacter denitrificans MT42)
MKRMLINATQREELRVAIVDGQNLYDLDIEIPSREQKKSNIYKGRITRVEASLEACFVEY
GAERHGFLPLKEISREYFTPGLDPHKANIRELIKEGQEVVVQVEKEERGNKGAALTTFIS
LAGRYMVLMPNNPKAGGVSRRIEGEDRQALKEALDHVTVPDDVGLIVRTAGLGRDAEELQ
WDLDYLLTLWKSISEAASKQKAPFLIYQESKLFIRALRDYLRSDIGEILIDDEPLYNDAR
DFMQQVMPNALRKLKLYRDDTPLFTRYQIETQIESAFDRQVRLPSGGSIVIDQTEALTAI
DVNSSKATKGSDIEETAFNTNCEAAVEIARQARIRDAGGLLVIDFIDMDSPKHQREVEDR
LKDALKLDRARVQIGRISRFGLLEMSRQRLRPSLGEATQITCPRCEGHGHIRGVESLSLS
TLRLIEEHAMKDNTGQVLVQAPTSVANFLLNEKRASVVEIELRHKAHVVIVADEKLETPH
IEIQRIREAEMGEHSKPSYERLTAVEASELPKMGQTLGSGEQPAVSGIVPASPAPVREEV
AAPVAAAAPPAARRQAAAAPAAAAPSGGIISRLFGWFRSAEAAAPAPIPKRVDNGGDGSS
RSRRDERGNRPGASSGAPSPRQPRREAAQQGSSKPSAQQPARGNRQRGNETQPRPAQQSQ
AQAARADRQPKPAAATENTPARAERKPNPPQSPKVERQPRITVDERPTAAPPDDAVKEAE
PLLAPLAASSVPESADSPLDAEGSQARRRRGRRGGRRRRRHDETATNGTDIDSALALDDE
DREEAIADATAATPVSHSAPSPRESSPVVAASDGDTAPAIVPARPPMPARPIETGTTPSI
DAEISATVPAATAFNLPTLPPIPDPVKSAVATAAADEHDLVRITPASTPAPEPQPAAVAM
SAGDSHATKADPLPMAVTIAATTPTTISRPASDTVSSTVVASSSTQPALAAVTAASPTVV
IPGSATASAPTAPFAQEVDPSMSVAVPAVATDKPESATDPVTSLQQPTQGDLLAQPNHPA
RPLPSLSEESEPASPRSHDESDAHKGDTNS