Protein Info for LRK55_RS17740 in Rhodanobacter denitrificans MT42

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 PF00072: Response_reg" amino acids 4 to 116 (113 residues), 88.7 bits, see alignment E=2.9e-29 PF00196: GerE" amino acids 146 to 201 (56 residues), 51.7 bits, see alignment E=5.5e-18

Best Hits

Swiss-Prot: 47% identical to GACA_PSEU2: Response regulator GacA (gacA) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: None (inferred from 54% identity to smt:Smal_1526)

Predicted SEED Role

"DNA-binding response regulator, LuxR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>LRK55_RS17740 response regulator (Rhodanobacter denitrificans MT42)
MINVVLVDDHELVRTGFRMILQQQPDIRVGGEAGSAEEGLHLIRSLAPDIALVDVHMPGM
SGIELTERVCRSKMSTHVVIVTVVDDARFPKRLLDAGALGYLTKGCSADELVSAVRQVAG
GRRYLAPAVAQQLALATLDGSASPFDVLSSRELEVAMMLVRGKPLTIIGEQLNLSPKTVS
TYKQRLMEKLHVDHVLSLAHLMTVHGLIDTPNHHVGN