Protein Info for LRK55_RS17085 in Rhodanobacter denitrificans MT42

Annotation: isoprenylcysteine carboxylmethyltransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 transmembrane" amino acids 21 to 45 (25 residues), see Phobius details amino acids 53 to 82 (30 residues), see Phobius details amino acids 113 to 143 (31 residues), see Phobius details amino acids 197 to 214 (18 residues), see Phobius details amino acids 226 to 242 (17 residues), see Phobius details PF04191: PEMT" amino acids 95 to 161 (67 residues), 48.7 bits, see alignment E=9.6e-17 PF04140: ICMT" amino acids 97 to 153 (57 residues), 29.7 bits, see alignment E=7.3e-11

Best Hits

KEGG orthology group: None (inferred from 48% identity to mes:Meso_1643)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (257 amino acids)

>LRK55_RS17085 isoprenylcysteine carboxylmethyltransferase family protein (Rhodanobacter denitrificans MT42)
MNTPPKKTSMPLRERIEQQGYWLFRWRSYLPLLLLPLFAFALRSYGQLEHAFGWLAGMGW
ELGCIALSFVGLLLRALTVGFVPAGTSGRNTSKQRADALNTTGIYSLVRHPLYLANFIGV
LGVLLFTESLWLTLTVTLIYWVYYERIMLAEEAFLREKYGEPYLRWAAATPALVPHFGNY
QPAAMPFSFRTVLQREYPSFFATVAAFTLIEWVGDWLGRHVFDHNPGWTAFFLAGFVIWL
ALRTLKKRRCLDVLGRQ