Protein Info for LRK55_RS16580 in Rhodanobacter denitrificans MT42
Annotation: protein phosphatase 2C domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01090, protein phosphatase [EC: 3.1.3.16] (inferred from 58% identity to smt:Smal_0846)Predicted SEED Role
"Protein serine/threonine phosphatase PrpC, regulation of stationary phase" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.1.3.16
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (233 amino acids)
>LRK55_RS16580 protein phosphatase 2C domain-containing protein (Rhodanobacter denitrificans MT42) MIEFGHGTHVGLRRTRNEDTYYADASLGLFLVADGMGGHQHGEVASALVRDGVVELVGKG HGLIEAVHAAAERLLAHTRPSFDVLPMGTTIAALRISGEGYEVAWVGDSRIYLWKKELRQ ISHDHSLVQALVEAGQLDPAQVAQHPQRNVLTQALGVTAIEQLHVGMARGQLEPGMGFLL CSDGLTEGVSDASIARVVARTDLAAQECVDQLLLSALDSGGDDNVTVLLVRSS