Protein Info for LRK55_RS16580 in Rhodanobacter denitrificans MT42

Annotation: protein phosphatase 2C domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 PF13672: PP2C_2" amino acids 14 to 193 (180 residues), 42.1 bits, see alignment E=1.2e-14 PF00481: PP2C" amino acids 23 to 126 (104 residues), 24.7 bits, see alignment E=2.6e-09

Best Hits

KEGG orthology group: K01090, protein phosphatase [EC: 3.1.3.16] (inferred from 58% identity to smt:Smal_0846)

Predicted SEED Role

"Protein serine/threonine phosphatase PrpC, regulation of stationary phase" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (233 amino acids)

>LRK55_RS16580 protein phosphatase 2C domain-containing protein (Rhodanobacter denitrificans MT42)
MIEFGHGTHVGLRRTRNEDTYYADASLGLFLVADGMGGHQHGEVASALVRDGVVELVGKG
HGLIEAVHAAAERLLAHTRPSFDVLPMGTTIAALRISGEGYEVAWVGDSRIYLWKKELRQ
ISHDHSLVQALVEAGQLDPAQVAQHPQRNVLTQALGVTAIEQLHVGMARGQLEPGMGFLL
CSDGLTEGVSDASIARVVARTDLAAQECVDQLLLSALDSGGDDNVTVLLVRSS