Protein Info for LRK55_RS16445 in Rhodanobacter denitrificans MT42

Annotation: trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 PF05697: Trigger_N" amino acids 1 to 144 (144 residues), 138.2 bits, see alignment E=3.9e-44 TIGR00115: trigger factor" amino acids 11 to 408 (398 residues), 340.9 bits, see alignment E=5e-106 PF05698: Trigger_C" amino acids 263 to 410 (148 residues), 87.5 bits, see alignment E=1.6e-28

Best Hits

Swiss-Prot: 35% identical to TIG_MARHV: Trigger factor (tig) from Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)

KEGG orthology group: K03545, trigger factor (inferred from 50% identity to psu:Psesu_2045)

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (430 amino acids)

>LRK55_RS16445 trigger factor (Rhodanobacter denitrificans MT42)
MQVSVENIGTLERKLTVKFPAERFETQVSARIAEMGRTVRLKGFRPGKVPTTVIKQRFGD
QVRGEVLSDLIGSTLREAVAQEKLQPIANPAIDTTGEPENGEIAYTATFEIMPEFPVVEV
AALEISRPMAVVTDADIDKMLETLRQQRRSFDEVDRASAEGDFVMFEYSAEAGDYRFPTE
GLERAGSVLGSGTLFKALDEALIGRKMGDSFETGIAFPEDFRNAQLAGKNAQVSFSILKV
QEPKLPEIDAEFAKLFGIADGDLETFRKEVRANLERELKAALMARLKSEVAEKLSLAHAG
LDVPKLMVQSEARNMAAGSVPQGQQPPPQLIEAAMPIARQRVIAGLLMGEIARKQEIKID
RKRVAEQLAAIASTYEEPEKVIELYNGDPQLMSGLQNRVMEDQVAEWVAEHAKTTQLDLS
FDDVMRPANA