Protein Info for LRK55_RS15830 in Rhodanobacter denitrificans MT42

Annotation: heme ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 transmembrane" amino acids 26 to 48 (23 residues), see Phobius details amino acids 68 to 88 (21 residues), see Phobius details amino acids 100 to 119 (20 residues), see Phobius details amino acids 133 to 152 (20 residues), see Phobius details amino acids 162 to 181 (20 residues), see Phobius details amino acids 201 to 221 (21 residues), see Phobius details PF01578: Cytochrom_C_asm" amino acids 10 to 188 (179 residues), 139.2 bits, see alignment E=7.7e-45 TIGR01191: heme exporter protein CcmC" amino acids 49 to 230 (182 residues), 252.7 bits, see alignment E=1.1e-79

Best Hits

Swiss-Prot: 53% identical to CCMC_HAEIN: Heme exporter protein C (ccmC) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02195, heme exporter protein C (inferred from 79% identity to xcv:XCV1715)

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>LRK55_RS15830 heme ABC transporter permease (Rhodanobacter denitrificans MT42)
MSDWIPLWLHKLSSPPTFYRFAGALQPWAMGLALLLGAVALYGGLVLAPADYQQGDAYRI
IFIHVPSAWMSMFIYAVMGAASFVALVWRIKLAEVVAMESAPIGAAFTFITLVTGSLWGK
PMWGTWWTWDARLTSELVLLFLFLGVIGLYHAFEDRRQGARAAAFLAIIGIINVPIVHFS
VNWWNTLHQGSTVNLFGQSKISAAMLWPLLTMTLATKFYYAASLFRRARTDLLALEGGKD
WVRKIAEDEADR