Protein Info for LRK55_RS15305 in Rhodanobacter denitrificans MT42

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 transmembrane" amino acids 6 to 29 (24 residues), see Phobius details amino acids 36 to 55 (20 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 94 to 112 (19 residues), see Phobius details amino acids 118 to 140 (23 residues), see Phobius details amino acids 152 to 176 (25 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 218 to 380 (163 residues), 134.5 bits, see alignment E=1.5e-43 PF00990: GGDEF" amino acids 222 to 377 (156 residues), 135.5 bits, see alignment E=7.2e-44

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (384 amino acids)

>LRK55_RS15305 GGDEF domain-containing protein (Rhodanobacter denitrificans MT42)
MHFDLFTLGVIGAAIGIAISISFTLLGLVLRGLPALRIWATAFWVITAAALTQGLNENGS
LLSTVVGGGLIALANALMLMGIAIHLRYPLRWRWPLAVVGLFVACQVDVYLSPPTQTVSA
LMFGGYSVVWDAWMVWVLLWRSPRDMRSTCSFTALIFIIDALFYLLRSVVVLFPQLLAHS
PLDELLTTWNYLFGILSSFLLSTGFTLMLAERLTLDLRRLARTDGLTGLLNRSALIEAGA
RLVDACRARGQGCSVLMFDLDHFKSINDNWGHAAGDAVLIHFVAVIRSVGLPRGTLFARY
GGEEFMLLLPAIEPAHAAALAERMRTAMAAAPAVFEGSRIDITTSVGGATAVDANVEQLV
NAADVALYRAKHQGRNQVAWNSEA