Protein Info for LRK55_RS14985 in Rhodanobacter denitrificans MT42

Annotation: S8 family serine peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 943 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF00082: Peptidase_S8" amino acids 74 to 360 (287 residues), 143.4 bits, see alignment E=1.5e-45 TIGR02601: autotransporter-associated beta strand repeat" amino acids 398 to 428 (31 residues), 24.8 bits, see alignment (E = 7.4e-10) PF12951: PATR" amino acids 399 to 427 (29 residues), 27.2 bits, see alignment (E = 4.8e-10) PF03797: Autotransporter" amino acids 672 to 923 (252 residues), 138.5 bits, see alignment E=5.6e-44

Best Hits

Predicted SEED Role

"Outer membrane stress sensor protease DegS" in subsystem Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (943 amino acids)

>LRK55_RS14985 S8 family serine peptidase (Rhodanobacter denitrificans MT42)
MNMLDSGLRRREMAWLVAMALGLSACGGGGNVKPTPPPTVPSSPPPGTPTGQPPLDAQLS
LTNAYAAHSLGYTGAGVTIGVVDSGIMRNHPALVGRVKQELLYVDPTANNTAIDDVVGHG
TWVSQIAAGGAFDKFPGGIAPAASLVSARIISDVAPKDDGSGQGNAVTAADAAFFAQTLN
PDLITAGVQVMNNSWGGIYWDTTKASINQAFAQAYEPFVLQHGGLVVFAAGNDSRSNPSD
IASLPSLAPQLGPGWLVAVAVDSNHPTQLASYSNACGRAMNYCLAAPGDVIVSDKGAVAG
VSPSYWVVSGTSFAAPEVSGAAALVWQAFPYFSNDLVRQTLLGTADDLGATGPDPVFGYG
ELNVGRAVNGPMKFDWGDVTVNFSGTSNWSNPINGAGGLIKQGSGTLNLIQPASYTGLTQ
VQGGTLNAKSLAGSVSIGAAGTLAGAQTILGDVTNAGVFGISGIAVGSDVVVGGNYVQQG
NGRLAVSLGSSLRIIGTASLAGGDLYVIGTNPGYVVNSHTNVLSAGGGLSGTFSALNKAS
NVVLLDATLNYDASSAWLDVTQVQATAVQGMTYTAASYGAAQRVDGAFGLINAQLGSGTA
ATGATPVATAFVAGAASLQQSASLAAAQHSLESLSGQLHAASAAMTFEAIDAGTRALSDR
FDSLLDAPQAGAWTQGLGYHGGMSRGGYEHVGYDLSGALVGQDLRVGGNGVAGYALSQSQ
GLGRLAESADQGRSHALEGMLYGGMIRGSWYTMGRFGIGNYRETMRRQLQLGNQFAGVAS
DVHGRYGVAYGESGYRFALGRTQLTPYMNLQYAQIRRDGFNELGAYGFGLKSAAQSTARW
QAGAGLRATREWALAGGGSLALQGRMLWQQSFGMRGEVFDASFSGINQFAPVGGIGLSRY
GGMLGTTLDWKMTPHASLQLGYDRYFGDRQQAQMGTVNFSWAF