Protein Info for LRK55_RS14795 in Rhodanobacter denitrificans MT42

Annotation: glycine cleavage system protein R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 PF13740: ACT_6" amino acids 19 to 90 (72 residues), 47.5 bits, see alignment E=1.4e-16 PF01842: ACT" amino acids 107 to 140 (34 residues), 27.8 bits, see alignment 1.7e-10

Best Hits

KEGG orthology group: K03567, glycine cleavage system transcriptional repressor (inferred from 59% identity to xac:XAC1759)

Predicted SEED Role

"Glycine cleavage system transcriptional antiactivator GcvR" in subsystem Glycine cleavage system or Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (191 amino acids)

>LRK55_RS14795 glycine cleavage system protein R (Rhodanobacter denitrificans MT42)
MKSSPGPSSASTRSGNDNQLLIHALTPTTKSPLLALAKRIADAGCNLSESRVSTIGTEIS
LMLLATGAWDALAKLETALAKLGRDESMRLVHYRTGPRQNSSHLLPYLVEVVAADRPGIV
ARIVDFFSQHGISVEQLNSTRYQAMQTGAEMFQAQFTIGIPAEIHIAALRDDFLELCDGL
NLDAIMDPVKF