Protein Info for LRK55_RS14245 in Rhodanobacter denitrificans MT42

Annotation: CPBP family glutamic-type intramembrane protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 51 to 82 (32 residues), see Phobius details amino acids 104 to 124 (21 residues), see Phobius details amino acids 143 to 165 (23 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 208 to 228 (21 residues), see Phobius details amino acids 235 to 254 (20 residues), see Phobius details PF02517: Rce1-like" amino acids 135 to 245 (111 residues), 38.2 bits, see alignment E=6.9e-14

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>LRK55_RS14245 CPBP family glutamic-type intramembrane protease (Rhodanobacter denitrificans MT42)
MPVQPPTLPVSGPHLKLAALFGIAGALATLALMPYAMALTPQKFTALPLPLPAIVLAAAA
QTGVLCWLLGWLGLYLGAPYGLDAPWLRAWVYRRPRDPARRPRWWLAVLLGGLAGLLVVG
LSALGPKHAENIIQAWRGALASFYGGIVEEVLCRLLLVSALVWLLARCNRRVARPWMFVL
AIVLAALLFGAGHLPAAHAAGLLGTPLLVARIVLLNAVVAVVFGGLFWKYGLEHAMLAHF
CADLVLHVALPLAGGF