Protein Info for LRK55_RS13935 in Rhodanobacter denitrificans MT42

Annotation: cation-translocating P-type ATPase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 842 transmembrane" amino acids 45 to 65 (21 residues), see Phobius details amino acids 71 to 87 (17 residues), see Phobius details amino acids 225 to 243 (19 residues), see Phobius details amino acids 254 to 280 (27 residues), see Phobius details amino acids 636 to 656 (21 residues), see Phobius details amino acids 663 to 684 (22 residues), see Phobius details amino acids 709 to 730 (22 residues), see Phobius details amino acids 742 to 759 (18 residues), see Phobius details amino acids 779 to 797 (19 residues), see Phobius details amino acids 803 to 828 (26 residues), see Phobius details PF00690: Cation_ATPase_N" amino acids 13 to 61 (49 residues), 36.5 bits, see alignment 8.9e-13 TIGR01494: HAD ATPase, P-type, family IC" amino acids 74 to 324 (251 residues), 121.1 bits, see alignment E=2.2e-39 amino acids 545 to 660 (116 residues), 110.1 bits, see alignment E=4.8e-36 PF00122: E1-E2_ATPase" amino acids 101 to 285 (185 residues), 132.1 bits, see alignment E=5.1e-42 PF00702: Hydrolase" amino acids 302 to 589 (288 residues), 66.9 bits, see alignment E=9.9e-22 PF12710: HAD" amino acids 483 to 586 (104 residues), 32.1 bits, see alignment E=4.8e-11 PF00689: Cation_ATPase_C" amino acids 659 to 830 (172 residues), 98.6 bits, see alignment E=1.1e-31

Best Hits

KEGG orthology group: K01537, Ca2+-transporting ATPase [EC: 3.6.3.8] (inferred from 69% identity to adk:Alide2_4667)

Predicted SEED Role

"FUPA30 P-type ATPase; putative cation-transporting ATPase pacL( EC:3.6.3.- )"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (842 amino acids)

>LRK55_RS13935 cation-translocating P-type ATPase (Rhodanobacter denitrificans MT42)
MSEAPPRLAGRPGLDPAEAARRLAEHGPNLLPGSTPKSLFGIVRGVLTEPMFLMLLVAGG
LYLALGDRAEAAFLLSAVFVVIGITLMQERKTQRALESLRELSAPRALVLRGGEEIRVPG
RDVVVGDLLVLHEGDRIAADALLLDGHLDVNESLLTGEAVPVTKLPGAEAGQLFASTVVT
KGVGVAEAHAVAGFTAVGRIGQALSTTVEPVSGLQLASRRLIRQLATGGLLLATAYALLG
WLWDGHGLLQSVLAGIALTMAILPEEIPVILTVFLALGAWRISRHKVLTRRIPAVETLGA
ISVLAVDKTGTLTQNRMQVAELDLVGDTFRDAGADELPEPFHELVEFAMLATPADPFDPM
EKAIQQFGLGWLTDTEHVHAEWAPEFEYALSPDILAMTRVFRGDARDAHLLATKGAPEAV
IDLCHLDAGQAAAILQRVEAMAERGLRVLGVARGEWQGAAWPRGQHDFDFRFLGLLGFVD
PPRPEVPAAIAECRGAGVRVIMMTGDHPATARAIAREVGLSERAEVITGAELAMLDDAAL
GERLRHVDLCARLQPEQKLRLVQLLRANGEVVAMTGDGVNDAPALKAADVGIAMGERGTD
VAREAAALVLLDDSFASIVSAIRQGRRIYDNITKATRFVFAVHMPIIALALVPTLLHWPV
LLMPVHIVLLELLIDPACSVVYEADPAADDIMQRPPRVPSDSPFAAANLRYAVIQGLGFA
GLLLLGYGLLLGQGLDAAQSRSAVFIALVAGLFLLTLANRDLSRPAFSRMPARNPWLPRM
FGAVALMLAAVVGLPFLRGVMGLAVPGALALLATAGMLAAAVVWLELLRRAAPGVARKAA
AR